Chapter 14: Liver Pathology

Many diseases can result in acute and/or chronic liver failure. This video for medical students explains the pathophysiology of these processes and provides a foundation for understanding the symptoms and diagnosis of these conditions.

This video for medical students focuses on three inherited metabolic liver diseases: hereditary hemochromatosis, Wilson disease and alpha 1 antitrypsin deficiency. There is a brief discussion of iron and copper metabolism, to provide a foundation for understanding the pathophysiology of these diseases. Morphologic findings and clinical features are discussed.

This video for medical students focuses on the pathophysiology of the two pathways to fatty liver disease: 1) excess alcohol (alcohol-related fatty liver disease) and 2) insulin resistance/metabolic syndrome (nonalcoholic fatty liver disease, NAFLD). Morphologic findings (steatosis, steatohepatitis & steatofibrosis/cirrhosis) and clinical features are also discussed.

This video for medical students begins with a review of bile formation/secretion and the features of cholestatic liver disease. Next, we compare and contrast two autoimmune cholangiopathies: primary biliary cholangitis and primary sclerosing cholangitis. There is a brief discussion of cholangiocarcinoma.