Chapter 3: Hemodynamic Disorders, Thromboembolism & Shock

Hemostasis can be a confusing and complicated topic so I've broken it down into two parts. This video will focus on initial endothelial injury to formation of the stable plug, covering the four phases of hemostasis: arteriolar vasoconstriction, primary hemostasis, secondary hemostasis and clot stabilization. We'll be working through this process using excellent illustrations by Dr. Abhijit Das for the 11th edition of Robbins and Kumar Basic Pathology.

This video will cover what happens after a clot has formed and will focus on the anticoagulant mechanisms employed by the body to prevent thrombosis.

This video will compare and contrast the 4 types of shock and do a deep dive into the pathophysiology of septic shock: inflammatory/counterinflammatory measures, endothelial activation and injury, induction of a procoagulant state, metabolic abnormalities and organ dysfunction.