Chapter 2: Inflammation and Repair

This video is an introduction to and overview of the confusing array of inflammatory mediators. IL-1, TNF, chemokines, leukotrienes, oh my! The goal of this video is to provide some context and a framework for thinking of these mediators so you can understand acute and chronic inflammation, autoimmune diseases and the medications used to treat these conditions. Also, a review of the systemic effects of inflammation and acute phase reactants!

This video focuses on the characteristic features of acute inflammation (vasodilation, increased permeability and emigration of leukocytes) are discussed as well as the possible outcomes of acute inflammation.

This video covers the different morphologic patterns of acute inflammation : serous, fibrinous and purulent inflammation as well as ulcers. The clinical implications of these various patterns are discussed.

This video focuses on chronic inflammation (including granulomatous inflammation) and tissue repair. Pathways to injury resolution including regeneration and scarring are discussed as well as factors that impair the healing process.